MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK
发明人:
PALESE, PETER,GARCIA-SASTRE, ADOLFO,O'NEIL, ROBERT
申请号:
CA2334850
公开号:
CA2334850C
申请日:
1999.06.11
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to novel methods and substrates for thepropagation of viruses. The invention relates to IFN-deficient substrates andmethods for propagating viruses in these unconventional substrates. Inparticular, the invention relates to methods of propagating viruses inimmature embryonated eggs, preferably six- to nine-day-old chicken eggs. Themethods of the invention are particularly attractive for growing virusessuitable for use in vaccine and pharmaceutical formulations.