Adolfo Garcia-Sastre;Peter Palese;Robert E. O'Neil
发明人:
Peter Palese,Adolfo Garcia-Sastre,Robert E. O'Neil,Robert E. ONeil
申请号：
US12364243
公开号：
US09352033B2
申请日:
2009.02.02
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates, to novel methods and substrates for the propagation of viruses. The invention relates to IFN-deficient substrates and methods for propagating viruses in these unconventional substrates. In particular, the invention relates to methods of propagating viruses in immature embryonated eggs, preferably six- to nine-day-old chicken eggs. The methods of the invention are particularly attractive for growing viruses suitable for use in vaccine and pharmaceutical formulations.
