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PHARMACEUTICAL FORM FOR ORAL ADMINISTRATION OF A HIGHLY CONTROLLED AND STABLE DOSE OF NANOPARTICLES OR BIOMACROMOLECULE SUSPENSIONS
专利权人:
发明人:
申请号:
EP17738073.0
公开号:
EP3403643A1
申请日:
2017.01.06
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The invention relates to the pharmaceutical industry, particularly to the pharmaceutical industry related to drugs comprising biomacromolecules, or biopharmaceuticals. Even more particularly, the invention relates to a pharmaceutical form comprising biomacromolecules such as lymphokines, hormones, haematopoietic factors, growth factors, antibodies, enzymes, inhibitors, vaccines, and DNA or RNA derivatives. The invention provides a pharmaceutical form comprising biomacromolecules and a method for producing same based on inkjet printing using inks formed by nanosystems comprising the biomacromolecule(s), the drug or biopharmaceutical being administered orally. Even more particularly, the invention relates to a pharmaceutical form for oral administration of a highly controlled, stable controlled release dose of a biomacromolecule comprising: a) a polymer film as a printing substrate, formed by at least one pharmaceutically acceptable excipient and b) an inkjet ink printed on the polymer film and comprising nanoparticles or nanoparticle suspensions comprising the biomacromolecule and at least one pharmaceutically acceptable excipient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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