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難溶性薬物の静注用分散製剤
专利权人:
株式会社;メドレックス
发明人:
松本 亘弘,▲浜▼本 英利
申请号:
JP2008200727
公开号:
JP5468221B2
申请日:
2008.08.04
申请国别(地区):
JP
年份:
2014
代理人:
摘要:

PROBLEM TO BE SOLVED: To render a drug sparingly soluble in water a dispersion preparation, particularly relating to an intravenous drip infusion preparation.

SOLUTION: To render a drug sparingly soluble in water a dispersion preparation, the dissolution of the drug in a composition comprising an ionic fluid of a fatty acid meglumine salt, ethanol, and water as essential components would enable the formation of a good dispersion preparation even if this composition (concentrated composition) is diluted and moreover, the dispersion preparation is found to be a stable dilute preparation. Thus, this injection composition (concentrated composition) can provide a preparation product of a drug sparingly soluble in water which is stable and has good dilution.

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