Mohammed Sharief;Michael J. Leach;Laurence S. Harbige;Paul Barraclough
发明人:
Laurence S. Harbige,Michael J. Leach,Mohammed Sharief,Paul Barraclough
申请号:
US13363705
公开号:
US20120142775A1
申请日:
2012.02.01
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A method is provided for treating a patient in need of therapy for a neurodegenerative disease comprising administering to that patient a therapeutically effective dose of a lipid glyceride comprising a glycerol moiety and a fatty acid moiety, the fatty acid moiety being selected from the group consisting of γ-linolenic acid, dihomo-γ-linolenic acid and arachidonic acid characterised in that the selected fatty acid moiety is attached to the glycerol moiety at its sn-2 position. Preferably the method is that wherein the lipid is administered for a duration and at a dose sufficient to maintain or elevate TGF-β1 levels in the patient to therapeutic levels.