PROCÉDÉS DE RÉDUCTION OU D'ÉLIMINATION DE LA MODIFICATION PROTÉIQUE ET DE LA DÉGRADATION PROTÉIQUE GÉNÉRÉES À PARTIR DE L'EXPOSITION À LA LUMIÈRE UV

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专利权人:

AMGEN INC;Amgen Inc.

发明人:

申请号：

EP12781248.5

公开号：

EP2771038B1

申请日:

2012.10.25

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Methods of inactivation of a virus in a sample comprising a protein component are provided. Also provided are methods of reducing protein degradation or modification in to the presence of a reactive species, such as a reactive species generated as a result of UV exposure, are also provided. In another aspect, a method of reducing oxidation of methionine residues, tryptophan residues or both methionine and tryptophan residues in a protein subjected to UV light is provided. The disclosed methods can be performed at any scale and can be automated as desired.

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http://www.ckcest.cn/home/