Martin Lehmann,Joshua Trueheart,Priscilla Zwart Jens,Liang Wu,Viktor Marius Boer,Cornelis Maria Jacobus Sagt,Manoj Kumar,Bernard Meijrink,Marco Alexander Van Den Berg
申请号：
US14373571
公开号：
US20150031868A1
申请日:
2013.01.23
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to a recombinant microorganism comprising one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl pyrophosphate synthase activity； a polypeptide having ent-Kaurene synthase activity； a polypeptide having ent-Kaurene oxidase activity； and a polypeptide having kaurenoic acid 13-hydroxylase activity, whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least steviol. The recombinant microorganism may also be capable of expressing one or more UDP-glucosyltransferases such that the microorganism is capable of producing one or more steviol glycosides.
