Kumar, Manoj,van den Berg, Marco Alexander,Boer, Viktor Marius,Lawrence, Adam G.,Lehmann, Martin,Meijrink, Bernard,Sagt, Cornelis Maria Jacobus,Trueheart, Joshua,Wu, Liang,Zwartjens, Priscilla
申请号：
AU2019204690
公开号：
AU2019204690A1
申请日:
2019.07.01
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
#$%^&*AU2019204690A120190718.pdf#####Abstract 5 DITERPENE PRODUCTION The present invention relates to a recombinant microorganism comprising one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl pyrophosphate synthase activity； a polypeptide having ent-Kaurene synthase activity； 10 a polypeptide having ent-Kaurene oxidase activity； and a polypeptide having kaurenoic acid 13-hydroxylase activity, whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least steviol. The recombinant microorganism may also be capable of expressing one or more UDP-glucosyltransferases such that the microorganism is capable of producing one 15 or more steviol glycosides.
