The invention relates to antibacterial compounds of formula Iwherein "-----" is a bond or is absent, V is CH, CR6or N； R0is H or, if "-----" is a bond, may also be alkoxy； R1is notably H or halogen； U is CH or N when "-----" is a bond, or, if "-----" is absent, U is CH2, NH or NR9； R2is H, alkylcarbonyl or -CH2-R3； R3is H, alkyl or hydroxyalkyl； R4is H or, if n is not 0 and R5is H, may also be OH； R5is H, alkyl, hydroxyalkyl, aminoalkyl, alkoxyalkyl, carboxy or alkoxycarbonyl； R6is hydroxyalkyl, carboxy, alkoxycarbonyl or -(CH2)q-NR7R8, q being 1, 2 or 3 and each of R7and R8independently being H or alkyl or R7and R8forming with the N atom bearing them a ring； R9is alkyl or hydroxyalkyl； A is -(CH2)p-, -CH2CH2CH(OH)- or - COCH2CH(OH)-； G is substituted phenyl or G1or G2wherein Q is O or S and X is CH or N； and Y1, Y2and Y3may each be CH or N； and n is 0 when A is -CH2CH2CH(OH)- or -COCH2CH(OH)-, and n is 0, 1 or 2 when A is -(CH2)p-, p being 1, 2, 3 or 4, with the proviso that the sum of n and p is then 2, 3 or 4； and to salts of such compounds.本發明係關於一種式I之抗細菌化合物，其中「-----」為一鍵或不存在，V為CH、CR6或N；R0為H，或若「-----」為一鍵，則R0亦可為烷氧基；R1尤其為H或鹵素；當「-----」為一鍵時，U為CH或N，或若「-----」不存在，則U為CH2、NH或NR9；R2為H、烷基羰基或-CH2-R3；R3為H、烷基或羥基烷基；R4為H，或若n不為0且R5為H，則R4亦可為OH；R5為H、烷基、羥基烷基、胺基烷基、烷氧基烷基、羧基或烷氧羰基；R6為羥基烷基、羧基、烷氧羰基或-(CH2)q-NR7R8，q為1、2或3且R7及R8各獨立為H或烷基，或R7及R8與攜帶其之N原子一起形成環；R9為烷基或羥基烷基；A為-(CH2)p-、-CH2CH2CH(OH)-或-COCH2CH(OH)-；G為經取代之苯基或G1或G2其中Q為O或S且X為CH或N；且Y1、Y2及Y3可各為CH或N；且當A為-CH2CH2CH(OH)-或-COCH2CH(OH)-時，n為0，且當A為-(CH2)p-，p為1、2、3或4時，n為0、1或2，但其限制條件為n與p之總和為2、3或4；及該等化合物之鹽。
