BOVIN, NICOLAI VLADIMIROVICH;HENRY, STEPHEN MICHEAL;KORCHAGINA, ELENA YURIEVNA;BOVIN; NICOLAI VLADIMIROVICH;TUZIKOV, ALEXANDER BORISOVICH;RODIONOV, IGOR LEONIDOVICH
发明人:
BOVIN, NICOLAI VLADIMIROVICH,HENRY, STEPHEN MICHEAL,KORCHAGINA, ELENA YURIEVNA,RODIONOV, IGOR LEONIDOVICH,TUZIKOV, ALEXANDER BORISOVICH
申请号：
EP12755058
公开号：
EP2675487A4
申请日:
2012.02.09
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Non-invasive method of monitoring by radioactivity bioscanning the distribution of a biological entity in a subject in vivo by administering to the subject a radioiodinated form of the biological entity. The radioiodinated form is prepared by contacting an aqueous suspension of the biological entity with a radioiodinated construct of the structure F-S-L where F comprises a radioiodinated tyrosine moiety, S is a spacer covalently linking F to L, and L is a lipid.
