Single step polymerization of covalently bound multilayer matrices

• 收藏
• 分享

专利权人:

The Regents of the University of California

发明人:

Adah Almutairi,Yogesh Ner,Jerome Karpiak,Jose Morachis

申请号：

US13794546

公开号：

US09409322B2

申请日:

2013.03.11

申请国别(地区):

US

年份:

2016

代理人:

摘要：

A method is provided for forming complex tissue using density gradient multilayer polymerization (DGMP) to form strong hydrogels with smooth transitions between layers. The multicompartment hydrogel is formed by co-dissolving a polymer precurser with a constituent in multiple solvent fractions to a create prepolymer solutions with different densities, layering the prepolymer solutions on top of each other from high to low solvent density, and irradiating the prepolymer solutions to form a polymer. The hydrogels may be used as biomimetic matrices.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/