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PROCESS FOR THE MANUFACTURING OF A MULTILAYER DRUG DELIVERY CONSTRUCT
专利权人:
DSM IP ASSETS B.V.
发明人:
John Andrew Zupancich,Julien François Berard
申请号:
US14432899
公开号:
US20150246001A1
申请日:
2013.10.23
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a process for the manufacturing of a multilayer construct comprising layering at least one drug loaded film from which each film comprises a polymer and at least a drug manufactured by the steps of dissolving the polymer in an organic solvent, mixing the dissolved polymer with the drug, laminating the mixture between at least two polymeric sheets, whereby at least one sheet is permeable to the organic solvent, removing the sheets to provide the drug loaded film, layering the drug loaded film and fusing the drug loaded films into a multilayer construct. The present invention also relates to the multilayer construct obtainable by the process according to the present invention and to the use of the multilayer construct in ophthalmology, cardiovascular, pain management, musculoskeletal, cancer treatment or in vaccine delivery.
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来源网址:
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