<;P>;PROBLEM TO BE SOLVED: To provide a new human peptide having osteoclast formation inhibition activity, and to provide a human osteoclast formation inhibition composition containing the peptide. <;P>;SOLUTION: The new human peptide having osteoclast formation inhibition activity is found from human Synovial membrane tissue. The human osteoclast formation inhibition composition contains the peptide. <;P>;COPYRIGHT: (C)2008,JPO&INPIT