A system and a method for acquiring image data of a subject with an imaging system is provided. The system can include a gantry that completely annularly encompasses at least a portion of the subject, which can be positioned along at an isocenter of the imaging system. The system can include a source and a detector positioned within and movable relative to the gantry on a rotor. The system can include a move control module that sets move data for each of the source, detector and rotor that causes the source, detector and rotor to move in a desired motion profile to acquire image data of a portion of the subject off the isocenter of the imaging system.