Pharmaceutical dosage form comprising 6’-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4’,9’-dihydro-3’h-spiro[cyclohexane-1,1’-pyrano[3,4,b]indol]-4-amine for the treatment of nociceptive pain
FRIEDRICH INGO,KIRBY CHRIS,GRÜNING NADJA,SCHILLER MARC,HEMANI ASHISH,BOTHMER JOHN,SCHOLZ ANDREAS
申请号:
NZ60588811
公开号:
NZ605888A
申请日:
2011.08.04
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is the use of a pharmaceutical dosage form containing a pharmacologically active agent formulated for oral administration once daily in the manufacture of a medicament for the treatment of nociceptive pain, wherein the pharmacologically active agent is selected from 6’-fluoro-N,N-dimethyl-4-phenyl-4’,9’-dihydro-3’H-spiro[cyclohexane-1,1’-pyrano[3,4-b]indol]-4-amine or 6’-fluoro-N-methyl-4-phenyl-4’,9’-dihydro-3’H-spiro[cyclohexane-1,1’-pyrano[3,4-b]indol]-4-amine (including cebranopadol) or a physiologically acceptable salt thereof; and which contains the pharmacologically active agent in a dose of from 150 µg to 800 µg, expressed as weight equivalent dosages based upon the free base.