The present invention discloses a clinical specimen sampler, including a filtering device and a sampling device. The sampling device includes a sampling adsorber and a rod. The sampling adsorber is connected with one end of the rod, and the sampling adsorber is encompassed in the filtering device. The sampling adsorber is utilized to absorb the body fluid secreted by the intima of an organ, and the filtering device is employed to prevent the mucosal tissue of the intima of the organ from entering the sampling adsorber and enable the body fluid secreted by the intima of the organ to enter the sampling adsorber, so as to be absorbed by the sampling adsorber.