IMPROVED SYNTHESIS OF NIR FLUORESCENT PROBE

• 收藏
• 分享

专利权人:

BRACCO IMAGING SPA

发明人:

Luciano LATTUADA,Federica BUONSANTI,Federico CRIVELLIN,Fulvio FERRETTI,Federico MAISANO,Laura ORIO,Lorena PIZZUTO

申请号：

US16604430

公开号：

US20200055855A1

申请日:

2018.04.10

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The application relates to a process for the synthesis of a Near Infra-Red (NIR) fluorescent probe which is a cRGD-Cy5.5 conjugate of formula (I) known as DA364 comprising an aza-bicycloalkane based cyclic peptide labelled with a Cy5.5 dye moiety and used in the guided surgery of tumors and pathologic regions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/