Composite granulated product and immediate release preparation containing low-substituted hydroxypropylcellulose

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专利权人:

信越化学工業株式会社

发明人:

丸山 直亮,平間 康之

申请号：

JP2016097208

公开号：

JP6195957B2

申请日:

2016.05.13

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

Provided is a base material for dry direct tableting, the material being excellent in a binding property and disintegrability. More specifically, provided is a method of preparing a composite granule comprising at least a step of granulating a second sugar or sugar alcohol while adding thereto an aqueous dispersion comprising at least low-substituted hydroxypropyl cellulose having a degree of hydroxypropoxy substitution of 5 to 16% by weight, polyvinyl alcohol, a first sugar or sugar alcohol, and water.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/