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Monolithic dosage form for the modified release of an active ingredient combination
专利权人:
Hennig Arzneimittel GmbH & Co. KG
发明人:
Gernot, Francas,Przyklenk, Karl-Heinz
申请号:
AU2013369379
公开号:
AU2013369379B2
申请日:
2013.12.23
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The invention relates to a monolithic peroral dosage form which allows a modified release, preferably an extended and delayed release, of an active ingredient combination of active ingredients with solubility properties that strongly deviate from one another. The dosage form comprises at least one emulsifier with a polyalkylene oxide structural motif and at least one controlled-release agent. Using the dosage forms according to the invention, even active ingredients which have a limited storage stability and other unfavorable active ingredient properties that additionally hinder processing can be featured in an optimal manner. The invention also relates to a method for producing the dosage form and to the use thereof.
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