БЕЙКЕР Стефен Дж. (US),САНДЕРЗ Вирджиния (US),АКАМА Цутому (US),БЕЛЛИНГЕР-КАВАХАРА Кэролин (US),ФРОЙНД Ивонне (US),МЕЙПЛЗ Керк Р. (US),ПЛАТТНЕР Джейкоб Дж. (US),ЧЖАН Юн-кан (US),ЧЖОУ Хучэнь (US),ЭРНАН
申请号：
RU2013152132/15
公开号：
RU2013152132A
申请日:
2013.11.22
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
A method of treating or preventing a human or animal disease associated with inflammation, said method comprising administering to a human or animal a therapeutically effective amount of a compound having a structure corresponding to formula I: wherein B is boron； R is a representative selected from the group consisting of negative charge, counterion salt, H, cyano, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl； M is a representative selected from oxygen, sulfur and NR； R is a representative selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl； J is a representative selected from (CRR) and CR； R, R and R are representatives, independently selected from the group consisting of H, cyano, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl； n1 is an integer selected from 0-2； W is a representative selected from C = O (carbonyl), (CRR), and CR； R, R, and R are representatives independently selected from the group consisting of H, cyano, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substitutedСпособ лечения или профилактики у человека или животного заболевания, связанного с воспалением, при этом указанный способ включает введение человеку или животному терапевтически эффективного количества соединения, имеющего структуру, соответствующую формуле I:,где B представляет собой бор；Rявляется представителем, выбранным из группы, вкл
