PROCEDES DE PREPARATION DE CONJUGUES

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专利权人:

IMMUNOGEN; INC.

发明人:

FISHKIN, NATHAN,MILLER, MICHAEL,LI, WEI,SINGH, RAJEEVA

申请号：

CA2825919

公开号：

CA2825919A1

申请日:

2012.02.15

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The present invention is directed to methods of preparing a conjugate of a cell-binding agent and a drug (such as a cytotoxic compound). The methods comprise the use of an imine reactive compound to enable efficient conjugations of cytotoxic compounds with cell binding agents.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/