Nathan Elliott Fishkin,Michael Louis Miller,Wei Li,Rajeeva Singh
申请号：
US15677846
公开号：
US10364294B2
申请日:
2017.08.15
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention is directed to methods of preparing a conjugate of a cell-binding agent and a drug (such as a cytotoxic compound). The methods comprise the use of an imine reactive compound to enable efficient conjugations of cytotoxic compounds with cell binding agents.
