您的位置: 首页 > 农业专利 > 详情页

COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING DISEASES CONDITION OR PROCESSES CHARACTERIZED BY ABERRANT PROLIFERATION OF FIBROBLASTS AND DEPOSITION OF THE EXTRACELLULAR MATRIX
专利权人:
ЛЭНДЕР Синтия (US); ИНК. (US);МОРИ МАТРИКС, ИНК. (US);МОРИ МАТРИКС;БРОФИ Колин (US)
发明人:
ЛЭНДЕР Синтия (US),БРОФИ Колин (US)
申请号:
RU2013150249/10
公开号:
RU2013150249A
申请日:
2012.04.12
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A pharmaceutical composition for use in the treatment of a disease, condition or pathological process characterized by aberrant fibroblast proliferation and deposition of an extracellular matrix in an individual's tissue, where the pharmaceutical composition contains a therapeutic amount of a YARAAARQARAKALARQLGVAA amino acid sequence polypeptide (SEQ ID NO: 1) or its functional equivalent and its functional equivalent a pharmaceutically acceptable carrier, also a therapeutic amount, is effective to reduce fibroblast proliferation and deposition of extra extracellular matrix in an individual's tissue. 2. The pharmaceutical composition of claim 1, wherein the disease or condition is acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). The pharmaceutical composition of claim 1, wherein the disease or condition is fibrosis caused by radiation. The pharmaceutical composition of claim 1, wherein the disease or condition is transplant rejection. The pharmaceutical composition of claim 1, wherein the tissue is lung tissue. The pharmaceutical composition of claim 1, wherein the disease or condition is an interstitial pulmonary disease. The pharmaceutical composition of claim 1, wherein the disease or condition is pulmonary fibrosis. The pharmaceutical composition of claim 7, wherein the pulmonary fibrosis is idiopathic pulmonary fibrosis. The pharmaceutical composition of claim 7, wherein pulmonary fibrosis develops as a result of administration of bleomycin. The pharmaceutical composition according to claim 7, where pulmonary fibrosis develops as a result of an allergic reaction, inhalation of substances in the form of1. Фармацевтическая композиция для применения в лечении заболевания, состояния или патологического процесса, характеризуемого аберрантной пролиферацией фибробластов и отложением внеклеточного матрикса в ткани индивида,где фармацевтическая композиция содержит терапевтическое количество полипептида аминокислотной последовательности YARAAARQ
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充