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Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
专利权人:
Moerae Matrix; Inc.
发明人:
Lander, Cynthia,Brophy, Colleen
申请号:
AU2015350151
公开号:
AU2015350151A1
申请日:
2015.11.17
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The described invention provides compositions and methods for reducing progression of a fibrosis in a tissue of a subject selected from liver, kidney or vascular fibrosis, the progression of the fibrosis being characterized by aberrant fibroblast proliferation and extracellular matrix deposition in the tissue. The method includes administering a therapeutic amount of a pharmaceutical composition containing a polypeptide having the amino acid sequence YARAAARQARAKALARQLGVAA (SEQ ID NO: 1) or functional equivalent thereof, and a pharmaceutically acceptable carrier, wherein the therapeutic amount of the polypeptide is effective to reduce progression of the fibrosis, to treat remodeling of the tissue, or a combination thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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