Peptide directed protein knockdown

• 收藏
• 分享

专利权人:

University of British Columbia

发明人:

Wang, Yu Tian,Lan, Shelly Xuelai,Jin, Wuyang Jin

申请号：

AU2013323101

公开号：

AU2013323101A1

申请日:

2013.09.27

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

In one aspect, the invention provides a peptide comprising a chaperone-mediated autophagy (CMA)-targeting signal domain； a protein-binding domain that selectively binds to a target cytosolic protein； and a cell membrane penetrating domain (CMPD). In another aspect, the invention provides methods for reducing the intracellular expression level of an endogenous target protein

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/