Sydney O. Ugwu,Vinay Radhakrishnan,Peter M. Ihnat,Leonore C. Witchey-Lakshmanan
申请号:
US14957653
公开号:
US20160082005A1
申请日:
2015.12.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
In its several embodiments, this invention discloses a pharmaceutical formulation comprising at least one antineoplastic agent or a pharmaceutically acceptable salt thereof, and at least one dissolution enhancing agent sufficient to substantially dissolve said at least one antineoplastic agent in at least one aqueous diluent, wherein said dissolution enhancing agent is urea, L-histidine, L-threonine, L-asparagine, L-serine, L-glutamine or mixtures thereof a lyophilized powder comprising said pharmaceutical formulation, and articles of manufacture thereof.