Sydney O. Ugwu,Vinay Radhakrishnan,Peter M. Ihnat,Leonore C. Witchey-Lakshmanan
申请号:
US15825296
公开号:
US20180078546A1
申请日:
2017.11.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
In its several embodiments, this invention discloses a pharmaceutical formulation comprising at least one antineoplastic agent or a pharmaceutically acceptable salt thereof, and at least one dissolution enhancing agent sufficient to substantially dissolve said at least one antineoplastic agent in at least one aqueous diluent, wherein said dissolution enhancing agent is urea, L-histidine, L-threonine, L-asparagine, L-serine, L-glutamine or mixtures thereof a lyophilized powder comprising said pharmaceutical formulation, and articles of manufacture thereof.