Vaccines comprising aluminium adjuvants and histidine

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专利权人:

Novartis Vaccines and Diagnostics S.r.l.

发明人:

Maffei, Massimo,Contorni, Mario

申请号：

AU2002330681

公开号：

AU2002330681C1

申请日:

2002.07.26

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

To improve the stability of vaccines comprising aluminium salt(s), the invention uses the amino acid histidine. This can improve pH stability and adjuvant adsorption and can be reduce antigen hydrolysis. Histidine is preferably presen during adsorption to the aluminium salt(s). The antigen in the vaccine may be a protein or a saccharide and is preferably from

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