PROBLEM TO BE SOLVED: To provide a tissue fastening apparatus that can impart to a coil an initial tension, which is the most suitable for making the two living tissues be in avascular necrosis by clamping and oppressing them so as to make them coalesce.SOLUTION: A tissue fastener manufacturing method of clamping two living tissues together by bringing the two living tissues into close contact includes: a step of fixing one end of a wire material made of a metal to a shaft body, and winding the wire material around an outer periphery of the shaft body while twisting the wire material round an axis of the wire material, thereby forming a coil a step of performing heat treating to impart superelasticity to the wire material and a step of deforming the wire material to which the superelasticity is imparted in a range in which the wire material is elastically deformable, and reversing the winding direction of the coil in a direction reverse to the winding direction of the coil wound in the step of forming the coil. In the manufacturing method, the initial tension in a compression direction of the coil acts on the coil after the step of reversing the winding direction of the coil.COPYRIGHT: (C)2013,JPO&INPIT【課題】2つの生体組織を挟み込んで圧迫により生体組織を虚血壊死させて、これら2つの生体組織を癒着させるために最適な初張力をコイルに付与することができる組織締結具を提供すること。【解決手段】2つの生体組織を密着させて締め付ける組織締付具の製造方法であって、以下の工程を含む。金属からなる線材の一端を軸体に固定し、前記線材の軸回りに前記線材をねじりつつ、前記軸体の外周に前記線材を巻いてコイルを成形する工程。前記線材に超弾性を付与する熱処理を行う工程。超弾性が付与された前記線材を、前記線材が弾性変形可能な範囲で変形させて、前記コイルの巻き方向を前記コイルを成形する工程で巻いた前記コイルの巻き方向と逆にする工程。この製造方法においては、前記コイルの巻き方向を逆にする工程の後に、前記コイルの圧縮方向への初張力が前記コイルに作用している。【選択図】図1
