MEDICAMENTS POUVANT SUBIR UNE OXYDO-REDUCTION DESTINES AU TRAITEMENT DES MALADIES MITOCHONDRIALES ET D'AUTRES AFFECTIONS ET MODULATION DE BIOMARQUEURS RELATIFS A L'ETAT ENERGETIQUE

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专利权人:

INC.;EDISON PHARMACEUTICALS

发明人:

MILLER, GUY M.,HECHT, SIDNEY M.

申请号：

CA2610152

公开号：

CA2610152C

申请日:

2006.06.01

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Methods of treating or suppressing mitochondrial diseases, such asFriedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON),mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), orKearns-Sayre Syndrome (KSS) are disclosed, as well as compounds useful in themethods of the invention, such as alpha- tocopherol quinone. Methods andcompounds useful in treating other disorders are also disclosed. Energybiomarkers useful in assessing the metabolic state of a subject and theefficacy of treatment are also disclosed. Methods of modulating, normalizing,or enhancing energy biomarkers, as well as compounds useful for such methods,are also disclosed.

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中国工程科技知识中心

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http://www.ckcest.cn/home/