2,3-fluorinated glycosides as neuraminidase inhibitors and their use as anti-virals

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专利权人:

The University of British Columbia

发明人:

Withers, Stephen,Watts, Andrew Graham,Kim, Jin Hyo,Wennekes, Tom

申请号：

AU2010273118

公开号：

AU2010273118B2

申请日:

2010.07.15

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

Compounds of structural formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza are provided Pharmaceutical preparations thereof and methods for their preparation are also described. The therapeutic effect is achieved via inhibition of viral neuraminidases, also known as viral sialidases. These neuraminidases are classified under the GH34 family of viral enzymes.

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