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2,3-fluorinated glycosides as neuraminidase inhibitors and their use as anti-virals
专利权人:
Stephen Withers
发明人:
Stephen Withers,Andrew Graham Watts,Jin Hyo Kim,Tom Wennekes
申请号:
US13382284
公开号:
US08815941B2
申请日:
2010.07.15
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Compounds of structural formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza are provided Pharmaceutical preparations thereof and methods for their preparation are also described. The therapeutic effect is achieved via inhibition of viral neuraminidases, also known as viral sialidases. These neuraminidases are classified under the GH34 family of viral enzymes.
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