The Regents of the University of Colorado, a Body Corporate;Musc Foundation for Research Development
发明人:
Holers, Michael V.,Tomlinson, Stephen
申请号:
AU2010202455
公开号:
AU2010202455B2
申请日:
2010.06.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2010202455B220130214.pdf#####ABSTRACT Modulation of the complement system represents a therapeutic modality for numerous pathologic conditions associated with complement activation. In a strategy to prepare 5 complement inhibitors that are targeted to sites of complement activation and disease, compositions comprising a complement inhibitor linked to complement receptor (CR) 2 are disclosed. The disclosed are compositions can be used in methods of treating pathogenic diseases and inflammatory conditions by modulating the complement system.