CHANG, MARGARET DAH TSYR,张大慈,張大慈,FAN, TAN CHI,范丹琪,LIN, SHU CHUAN,林淑娟
申请号：
TW097145067
公开号：
TWI359664B
申请日:
2008.11.21
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
A method for reducing cytotoxicity of eosinophil derived toxins comprising administering to a subject an effective amount of heparin, heparan sulfate, a potent heparanase inhibitor or a polypeptide which has sequence as follows: BZBXBX, XBBBXXBX, XBBXBX, BBXXBBBXXBB, BXBBXB, XBBBXXBBBXXBBX, or TXXBXXTBXXXTBB, wherein X represents any amino acid, Z represents an aromatic amino acid, and B represents a basic amino acid and T represents a turn.一種降低嗜酸性球毒素之組合物，其包含肝素、有效的肝素分解酵素抑制劑、或是含有以下序列的多肽：BZBXBX、XBBBXXBX,XBBXBX、BBXXBBBXXBB、BXBBXB、XBBBXXBBBXXBBX或TXXBXXTBXXXTBB，其中X為任何胺基酸、Z為芳香族胺基酸、B為鹼性胺基酸、T則為轉折。
