ORNA GRIBOVA;ALEXANDER VOL;OSHADI DRUG ADMINISTRATION LTD.
发明人:
ALEXANDER VOL,ORNA GRIBOVA
申请号:
IL20683410
公开号:
IL206834A
申请日:
2010.07.06
申请国别(地区):
IL
年份:
2015
代理人:
摘要:
The present invention provides a pharmaceutical composition formulated for oral delivery of insulin, comprising a particulate non-covalently associated mixture of pharmacologically inert silica nanoparticles having a hydrophobic surface, a polysaccharide, and insulin suspended in an oil. The present invention further provides methods of manufacturing same and therapeutic methods utilizing same for oral delivery of insulin.