A method for preparing a red yeast rice and a red yeast rice prepared by the same are provided to suppress a cholesterol level without liver damage and kidney damage. In a method for preparing a red yeast rice and a red yeast rice, the rice is put into a culture bag and solid medium is manufactured. A strains of the genus Monascus is inoculated with a solid medium and it is cultivated. The cultivation is performed for a first period under a first temperature and for a second period under a second temperature. In manufacturing cultivation envelope solid medium, the rice less than 1kg is put into the culture bag and it is increased. The first temperature is 31‹C, and the second temperature is 28‹C.홍국의 제조 방법 및 이에 의해 제조된 홍국이 제공된다. 상기 홍국의 제조 방법은 쌀을 배양봉투에 담아 증자하여 고체배지를 제조하는 단계 및 고체배지에 모나스커스속 균주를 접종하여 배양하되, 제1 온도에서 제1 기간 동안 배양하고, 제1 온도보다 낮은 제2 온도에서 제2 기간 동안 배양하는 단계를 포함한다.