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PHENOL COMPOUNDS WITH IMPROVED ELECTROPHILIC PROPERTIES FOR TREATMENT OF INFLAMMATORY DISEASES AND DISORDERS
专利权人:
ГЛОБАЛ БИОЛАЙФ ИНК. (US)
发明人:
ТОМПСОН, Дарил, Ли (US)
申请号:
RU2018141590
公开号:
RU2018141590A
申请日:
2017.05.16
申请国别(地区):
RU
年份:
2020
代理人:
摘要:
A therapeutic compound has a modified phenolic compound of the general formula (I) wherein at least one of R, R1, R2, R3, and R4 is an electrophilic group chosen fromhalogen, aldehyde, haloalkane, alkene, butyryl, flurophenol, sulfonamide, flurophenol sulfoxide and the remaining R, R1, R2, R3, and R4 is are each independently hydrogen, a hydroxyl group, an alkoxy group, a rutinosyl group, a carboxyl group, chromone, benzopyran, a rhamnosyl group, a substituted alkoxy group or a substituted acyloxy group wherein the substituent is chosen from hydroxyl, alkoxy, aryloxy, phenyl, halogen, and amido group. The compound can be used in a therapeutic treatment of inflammatory related diseases and condition.
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