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Electrophilically enhanced phenolic compounds for treating inflammatory related diseases and disorders
专利权人:
GLOBAL BIOLIFE INC.
发明人:
Daryl Lee Thompson
申请号:
US15156021
公开号:
US10123991B2
申请日:
2016.05.16
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A therapeutic compound has a modified phenolic compound of the general formula (I)wherein at least one of R, R1, R2, R3, and R4 is an electrophilic group chosen from halogen, aldehyde, haloalkane, alkene, butyryl, flurophenol, sulfonamide, flurophenol sulfoxide and the remaining R, R1, R2, R3, and R4 is are each independently hydrogen, a hydroxyl group, an alkoxy group, a rutinosyl group, a carboxyl group, chromone, benzopyran, a rhamnosyl group, a substituted alkoxy group or a substituted acyloxy group wherein the substituent is chosen from hydroxyl, alkoxy, aryloxy, phenyl, halogen, and amido group. The compound can be used in a therapeutic treatment of inflammatory related diseases and condition.
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