A medical manipulator system has an operating unit including a grip handle and a composite input unit, a working unit detachably mounted on the operating unit and including an end effector, and a controller for controlling the operating unit. The controller judges starting and ending of a surgical case and increments the usage count of the working unit based on a manner in which the working unit is mounted and dismounted, and the times at which the working unit is mounted and dismounted, and disables the working unit if the usage count of the working unit exceeds a preset count.