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ISOXAZOLES ET LEUR UTILISATION EN TANT QUE MODULATEURS DU RECEPTEUR-5 DE GLUTAMATE METATROPIQUE
专利权人:
ASTRAZENECA AB;NPS PHARMACEUTICALS, INC.
发明人:
WENSBO, DAVID,STORMANN, THOMAS M.,MCLEOD, DONALD A.,KERS, ANNIKA,MALMBERG, JOHAN,OSCARSSON, KARIN,GYBACK, HELENA,JOHANSSON, MARTIN,MINIDIS, ALEXANDER,WALDMAN, MAGNUS,YNGVE, ULRIKA,OSTERWALL, CHRISTOFF
申请号:
CA2494987
公开号:
CA2494987C
申请日:
2003.08.08
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to new compounds of formula (I), a process fortheir preparation and new intermediates prepared therein, pharmaceuticalformulations containing said compounds and to the use of said compounds intherapy. In particular, there are compounds according to the present inventionthat are potent and selective for the mGluR Group I receptor and moreparticularly for mGluR5. Thus, it is expected that the compounds of theinvention are well suited for the prevention and/or treatment of mGluR5receptor-mediated disorders such as acute and chronic neurological andpsychiatric disorders and chronic and acute pain disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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