Frantisek Hubalek,Thomas Hoeg-Jensen,Ib Jonassen,Patrick William Garibay,Palle Jakobsen,Svend Havelund,Janos Tibor Kodra
申请号:
US12297911
公开号:
US08933021B2
申请日:
2007.05.08
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to novel human insulin derivatives which are soluble at physiological pH values and have a prolonged profile of action. The invention also relates to methods of providing such derivatives, to pharmaceutical compositions containing them, to methods of treating diabetes and hyperglycaemia using the insulin derivatives of the invention and to the use of such insulin derivatives in the treatment of diabetes and hyperglycaemia.