The purpose of the present invention provides a kind of plastic cement ampoule in what, and the volatilization that can inhibit medical fluid scatters and disappears or plastic cement blender is dissolved out into medical fluid, and can inhibit the deformation damage that burr or opening portion are generated when plastic cement ampoule breaks a seal. The plastic cement ampoule 10 of the present invention has: the medical fluid receiving portion 11 to accommodate medical fluid； It is connected to medical fluid receiving portion 11 and canister portion 12 is discharged to the medical fluid of side extension； And the top 13 of one of closing medical fluid discharge canister portion 12 side end； And medical fluid discharge canister portion 12 has the frangible portion 14 for being circumferentially formed as thin-walled. Above-mentioned medical fluid receiving portion 11, medical fluid discharge canister portion 12 and 13 system of top are formed by multi-layer plastic, which has: the middle layer containing the cycloolefin (co) polymer that glass transition temperature is 60 ~ 80 DEG C； The internal layer of lamination what middle layer inside； The outer layer in lamination what middle layer outside； And the adhesion layer of what middle layer and interior interlayer and outer layer and intermediate interlayer is respectively configured.本發明之目的在於提供一種塑膠安瓿，其可抑制藥液之揮發．散失、或塑膠調配劑溶出至藥液中，並可抑制塑膠安瓿開封時產生毛刺、或開口部之變形．損壞。本發明之塑膠安瓿10具備：用以容納藥液之藥液容納部11；與藥液容納部11連通並向一側延伸之藥液排出筒部12；及封閉藥液排出筒部12之一側端部之頂部13；並且藥液排出筒部12具備沿著圓周方向形成為薄壁之脆弱部14。上述藥液容納部11、藥液排出筒部12及頂部13係由多層塑膠形成，該多層塑膠具備：含有玻璃轉移溫度為60~80℃之環狀烯烴系(共)聚合物之中間層；積層於中間層內側之內層；積層於中間層外側之外層；以及分別配置於中間層與內層間、及外層與中間層間之黏著層。
