SOURIS AYANT DES SEGMENTS DE GENES VARIABLES LAMBDA HUMANISES

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专利权人:

Inc.;Regeneron Pharmaceuticals

发明人:

申请号：

EP17162880.3

公开号：

EP3205726A1

申请日:

2011.06.22

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

A transgenic mouse is provided comprising in its genome an endogenous λ light chain immunoglobulin locus comprising a deletion of the endogenous mouse Vλ1-Jλ3-Cλ3-Jλ1-Cλ1 gene cluster and a deletion of a region spanning from Vλ2 to Jλ2 of the endogenous mouse Vλ2-Vλ3-Jλ2-Cλ2-Jλ4-Cλ4 gene cluster. Mouse cells and mouse embryos are also provided.

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中国工程科技知识中心

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http://www.ckcest.cn/home/