A circuit and method for long term electrocardiogram (ECG) monitoring is implemented with the goal of reducing power consumption, battery size, and consequently device size. In one embodiment, the integrated circuit includes an amplifier cell having a plurality of input terminals and an output terminal a QRS amplifier cell in communication with the output of the amplifier cell a baseline amplifier cell in communication with the output of the amplifier cell a comparator cell having a first input terminal in communication with the output terminal of the QRS amplifier cell and a VDC cell having an input in communication with the output of the baseline amplifier cell and an output in communication with the second input terminal of the comparator cell, wherein the comparator cell generates an output pulse in response to the output signal from the amplifier cell and the output signal from the baseline amplifier cell.
