ESSLINGER, CHRISTOPH,KUENZLE, SANDRA,ABELA, IRENE,ZIPPELIUS, ALFRED,JAEGER, DIRK,KNUTH, ALEXANDER,NITSCH, ROGER, M
申请号：
NZ57952008
公开号：
NZ579520A
申请日:
2008.03.13
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed is a human, humanized, murine, xenogeneic or chimeric human-murine antibody or binding fragment thereof which is capable of recognizing tumor-associated antigen NY-ESO-l, comprising in its variable heavy chain region the complementarity determining regions CDR1 of SEQ ID NO:5, CDR2 of SEQ ID NO:6, and CDR3 of SEQ ID NO:7 and in its variable light chain region the complementarity determining regions CDR1 of SEQ ID NO:8, CDR2 of SEQ ID NO:9 and CDR3 of SEQ ID NO: 10, or a CDR2 and CDR3 which differ by one, two, or three amino acids from SEQ ID NO:6, 7, 9 or 10.
