The Regents of The University of Michigan;Indiana University Research & Technology Corporation
发明人:
LARSEN, Scott D.,HUDDLE, Brandt C.,YANG, Kun,BUCKANOVICH, Ronald,HURLEY, Thomas
申请号:
EP17816061
公开号:
EP3471712A4
申请日:
2017.06.20
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a thiopyrimidinone structure which function as inhibitors of ALDH protein, and their use as therapeutics for the treatment of cancer and other diseases.