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NITRIC OXIDE DONOR NEPRILYSIN INHIBITORS
专利权人:
Mathai Mammen;Adam D. Hughes
发明人:
Mathai Mammen,Adam D. Hughes
申请号:
US13905338
公开号:
US20130323271A1
申请日:
2013.05.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
In one aspect, the invention relates to compounds having the formula:where R1, R2, R3, R7, R8, Z, X, b, and c are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds are nitric oxide donors and have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
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