PROBLEM TO BE SOLVED: To provide a solid preparation which has excellent disintegration properties and suspension properties in water, allows homogeneous dispersion of drug granules in a small amount of water, exhibits good extrudability from a glass syringe and, therefore, can minimize the amount of the drug remaining in the glass syringe while preventing a feeding tube from blocking up with the drug granules.SOLUTION: There is provided a solid preparation which comprises two or more kinds of disintegrating agents selected from the group consisting of crospovidone, croscarmellose sodium, croscarmellose calcium, low-substituted hydroxypropyl cellulose, low-substituted sodium carboxymethyl starch, crystalline cellulose, pregelatinized starch, starch and povidone.COPYRIGHT: (C)2012,JPO&INPIT【課題】水中での崩壊性及び懸濁性に優れ、薬物顆粒を少量の水に均一に分散でき、かつ、注射筒からの押出し性が良好で、経管チューブが薬物顆粒で詰まることがなく注射筒内に残存薬剤を少なく抑える固形製剤を提供する。【解決手段】クロスポビドン、クロスカルメロースナトリウム、クロスカルメロースカルシウム、低置換度ヒドロキシプロピルセルロース、低置換度カルボキシメチルスターチナトリウム、結晶セルロース、アルファ化デンプン、デンプン、ポビドンからなる群から選ばれる2種以上の崩壊剤を含む固形製剤。【選択図】なし
