PROBLEM TO BE SOLVED: To provide in-oral cavity disintegrable tablets with smooth tongue touch, reduced in powderiness attributable to water absorption and having moderate strength and quick in-oral cavity disintegrability.SOLUTION: The in-oral cavity disintegrable tablets each comprises (a) a partially pregelatinized starch, (b) a nonswelling and sparingly water-soluble inorganic salt and (c) a water-soluble excipient wherein the mass ratios (b)/(a) and (c)/(a) are 3 to 7 and 7 to 15, respectively, and the total amount of the ingredients(a), (b) and (c) is 60 mass% or greater based on the whole tablet.COPYRIGHT: (C)2008,JPO&INPIT【課題】崩壊剤の吸水による粉っぽさを低減し、しかも適度な強度と口腔内での速やかな崩壊性を有する、舌触りが良好な口腔内崩壊錠を提供する。【解決手段】(a)部分α化デンプン、(b)非膨潤性水難溶性無機塩及び(c)水溶性賦形剤を含有する口腔内崩壊錠であって、(b)/(a)(質量比)=3~7、(c)/(a)(質量比)=7~15、かつ(a)、(b)及び(c)成分の合計量が崩壊錠全体の60質量%以上である口腔内崩壊錠。【選択図】なし
