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METHOD OF DIAGNOSING PANCREATIC ADENOCARCINOMA AND METASTASES IN ITS PARENCHYMA
专利权人:
federalnoe gosudarstvennoe byudzhetnoe uchrezhdenie "Rostovskij nauchno-issledovatelskij onkologicheskij institut" Ministerstva zdravookhraneniya Rossijskoj Federatsii
发明人:
Kit Oleg Ivanovich (RU),Кит Олег Иванович (RU),Frantsiyants Elena Mikhajlovna (RU),Франциянц Елена Михайловна (RU),Iozefi Dmitrij Yaroslavovich (RU),Иозефи Дмитрий Ярославович (RU),Vinidchenko Mikhail
申请号:
RU2018122336
公开号:
RU0002699277C1
申请日:
2018.06.18
申请国别(地区):
RU
年份:
2019
代理人:
摘要:
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to magnetic resonance imaging, abdominal surgery and gastroenterology, and can be used for diagnosing pancreatic (PG) adenocarcinoma and metastases in its parenchyma. Magnetic resonance examination of abdominal organs in T2- and DWI-weighted sequences with calculation of ADC for positioning of pancreas, visualization of general anatomy, determination of direction of pancreatic and common bile ducts. Transpancreatic T2-weighted sequence is performed, sections of which are laid through the pancreas parallel to the Wirsung duct location. For this purpose oblique T2-weighted image with TE in range of 80–90, TR – 9400-9500 is used, matrix resolution is not lower than 320×192. Note here that slice thickness should be 3–4 mm while spacing is set to 0 mm between cuts. Function of triggering data collection on coinciding respiratory triggering or respiratory standstill is used. Number of cuts must be sufficient for imaging the entire pancreas. T2-weighted image of the PG with a duct system is obtained. Presence of PG tumour is detected, which violates the permeability of the duct system with its suprastenotic expansion of the caudal tumour, or metastases in its parenchyma and their mutual arrangement with the duct system. Then, isovoxel DWI-sequence with b 0 and b 1000 is laid in a similar manner in parallel to the Wirsung duct, which reduces the number of artefacts and averaged data in postprocessing on the boundaries of the tissue media in the planes perpendicular to the sections of interest. Then, a summation – FUSION – image of a PG with a tumour or metastases in its parenchyma is obtained, using the ADC of the isovoxel DWI-sequence with b 0 and b 1000 and the transpancreatic T2-sequence. In the presence of hyperintense MP-signal in DWI, limiting diffusion to 0.0008–0.0014 mm2/s in a tumour, iso-hypertensive MP-signal in transpancreatic T2-sequence with violation of permeability of duct system of PG is diagn
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